Gordon Lithgow, Ph.D.
Dr. Lithgow received his PhD in Genetics from the University of Glasgow, Scotland. He completed postdoctoral training at the Institute for Behavioral Genetics at the University of Colorado, Boulder. Dr. Lithgow was a Senior Lecturer in Molecular Gerontology at the School of Biological Sciences at the University of Manchester in England before coming to the Buck Institute in 2001.
He is the Principal Investigator and Director of the Buck Institute’s Interdisciplinary Research Consortium on Geroscience. He is also the Principal Investigator of the Larry L. Hillblom Network on the Chemical Biology of Aging, and is the Coordinator of the Hillblom Center for the Biology of Aging Support Award.
Dr. Lithgow sheds light on the mechanisms of aging by identifying agents that extend lifespan or prevent age-related disease.
The Lithgow lab has made seminal discoveries in the use of pharmacological agents to intervene in aging processes, such as antioxidants that protect cells against damage from unstable chemicals called free radicals. More recently, his lab has uncovered compounds that act as “stress response mimetics” that maintain protein balance and stability. These compounds suppress pathology associated with Alzheimer’s disease. The lab continues to undertake screens for chemical compounds that slow aging and extend healthspan.